« Older Entries

Male Organ Skin Discoloration: Is Vitiligo the Cause?

Many men have questions concerning male organ skin discoloration, mostly those who notice that there is some variation in color across their members, or that their male organs are a different color than the rest of their bodies. These cases are not unusual and are generally natural and harmless. But for some men, male organ discoloration occurs in the form of vitiligo, a condition that causes patches of skin to lose pigmentation and turn white or lighter than the surrounding skin. Does this affect male organ health? What can men do about it? The following information on vitiligo can help men get their bearings.

What is it?

Vitiligo occurs when cells in the body that normally produce skin color, called melanocytes, either stop working properly or die. Some people also experience the lightening effect on their hair and eyeballs, not just the skin. The causes of vitiligo are poorly understood, but the following are believed to be potential sources:

• Heredity
• Immune system dysfunction in which it attacks melanocytes
• Stress
• Sunburn
• Exposure to chemicals

The condition affects individuals differently. Some people have many affected body parts; others may have only one body part or side of the body affected; still others may have the condition on a few nearby parts. Sometimes, the condition progresses rapidly; sometimes it goes on for many years; other times, it stops after a year or two. It’s rare for pigmentation to return.

Is it dangerous?

Yes and no. The white patches cause no physical harm. However, people with vitiligo may be more at risk for sunburn, skin cancer, hearing loss and eye issues. It’s important to keep affected skin protected from the sun. Finally, social and psychological distress may occur as people often feel self-conscious about the effects of the condition.

Is there a cure?

No. There is currently no way to revive melanocytes or make them begin to produce pigment again.

Are there ways to manage it?

Yes, although many of them come with side effects.

A simple at-home management strategy that some people with vitiligo use is a topical self-tanner or makeup to conceal the lightened skin. For men with male organ vitiligo, their skin may be too sensitive for this option – not to mention, it might interfere with sensual activities.

Corticosteroid creams can alleviate some of the lightening; however, they tend to make skin thinner over time, and can cause lines to form on the skin.

Immune system medications are sometimes used. These medicines may increase a person’s risk of skin cancer and lymphoma.

Some people are treated with ultraviolet light. Again, for the male organ, this may be too harsh, as the treatment can cause dryness and itchiness on less delicate skin.

These are only some of the common treatments used in the management of vitiligo. Men and their doctors should discuss the risks associated with any option before choosing to try it. Also discuss alternative medicine options, including ginko biloba, folic acid and vitamin B-12.

How will it affect a man’s sensual life?

One factor determining the answer to this question is a man’s own self-consciousness. If he has anxiety about exposing his male organ to a partner, he’s bound to have a more difficult sensual life.

Speaking openly about the condition can help partners feel at ease about sensual activity. While there’s no reason for men to feel ashamed or embarrassed about the condition, most people don’t know what it is and potential sensual partners are bound to have questions. Approaching these with knowledge and information will help. If a partner has further concerns, he or she can easily access information from reputable sites online.

Optimal skin care

Given the side effects of many vitiligo management options, men may find it best to simply accept their male organs as they are. Maintaining good skin condition is important, and whether a man has vitiligo or not, he would do well to invest in skin care, particularly if he has dry skin. And the male organ is not immune to this, as many men know. Employing a quality male organ health crème (health professionals recommend Man1 Man Oil) will provide moisture as well as nutrients that support good circulation and nerve health. A better look and feel can be attained with Man1 Man Oil. Remember, healthy skin is what counts, regardless of its color(s).

Visit http://www.menshealthfirst.com for additional information on most common male organ health issues, tips on improving organ sensitivity and what to do to maintain a healthy member. John Dugan is a professional writer who specializes in men’s health issues and is an ongoing contributing writer to numerous websites.

—

Tags:

Introduction to Catalytic Characteristics of Enzymes

As biocatalysts, enzymes and general catalysts are the same in many respects. For example, the amount is small but the catalytic efficiency is high. Like general catalysts, enzymes can only change the speed of chemical reactions, not the equilibrium point of chemical reactions. The enzyme itself does not change before and after the reaction, so the relatively low content of the enzyme in the cell can catalyze the change of a large number of substrates in a short time, reflecting the high efficiency of enzyme catalysis. Enzymes can reduce the activation energy of the reaction, but do not change the free energy change (³G) during the reaction, thus speeding up the reaction and shortening the time for the reaction to reach equilibrium, but it does not change the equilibrium constant.

Compared with general catalysts, the catalysis of enzymes shows unique characteristics.

1. High efficiency of enzyme catalysis

The catalytic activity of enzymes is much higher than that of chemical catalysts. For example, catalase (containing Fe2+) and inorganic iron ions both catalyze the decomposition reaction of hydrogen peroxide as follows. 1 mol of catalase can catalyze the decomposition of 5×106 mol of H2O2 in 1 minute. Under the same conditions, 1 mol of the chemical catalyst Fe2+ can only catalyze the decomposition of 6×10-4 mol of H2O2. Compared with the two, the catalytic efficiency of catalase is about 1010 times that of Fe2+.

The level of enzyme catalytic efficiency can be expressed by the concept of turnover number. The conversion number refers to the number of molecules per enzyme molecule that can convert the substrate per minute when the substrate concentration is large enough, that is, the number of molecules that catalyze the chemical change of the substrate. According to the data introduced above, the conversion number of catalase can be calculated as 5×106. The conversion number of most enzymes is around 1,000, and the largest can reach over 106.

(2) High specificity of enzyme catalysis

An enzyme can only act on a certain type or a specific substance. This is the specificity of enzyme action. For example, glycosidic bonds, ester bonds, peptide bonds, etc. can be hydrolyzed by acid-base catalysis, but the enzymes that hydrolyze these chemical bonds are different. They are the corresponding glycosidases, esterases, and peptidases, that is, they are individually specific. It can be hydrolyzed by natural enzymes.

(3) Mild reaction conditions catalyzed by enzymes

Enzymatic reactions generally require mild conditions such as normal temperature, normal pressure, and neutral pH. Because enzymes are proteins, they are prone to lose their activity in environments such as high temperature, strong acid, and alkali. Since enzymes are more sensitive to changes in the external environment and are easily denatured and inactivated, the reaction conditions must be strictly controlled during application.

(4) Adjustability of enzyme activity

Compared with chemical catalysts, another feature of enzyme catalysis is that its catalytic activity can be automatically regulated. Although there are many kinds of chemical reactions in organisms, they are very coordinated and orderly. Changes in substrate concentration, product concentration and environmental conditions may affect enzyme catalytic activity, thereby controlling the coordinated and orderly progress of biochemical reactions. Any disorder and imbalance of the biochemical reaction will inevitably cause the organism to produce disease or even death in severe cases. In order to adapt to changes in the environment and maintain normal life activities, organisms have formed a system that automatically regulates enzyme activities during the long evolutionary process. There are many ways to regulate enzymes, including inhibitor regulation, feedback regulation, covalent modification regulation, zymogen activation, and hormone control.

(5) Enzyme catalytic activity is related to coenzyme, prosthetic group and metal ion

Some enzymes are complex proteins, and the small molecules of coenzymes, cofactor and metal ions are closely related to the catalytic activity of the enzyme. If they are removed, the enzyme loses its activity.

Tags:

Can Blockchain Technology Effect The Genomics Industry?

Most of the time, Blockchain technology is considered with cryptocurrencies like bitcoins, Litecoin, Ethereum, EOS, etc. However, that’s not the case today!In fact, the blockchain has become a different industry with an aim to protect and secure all types of data. very different. The past few years were really very exciting for traders with blockchain technology all over the world.Many companies worldwide in different industries integrated their data with blockchain, which in return gave them better results before their expectations.However, one industry that gained significant adhesion by implementing blockchain technology is the Genomic Data Industry. Yes, the industry that keeps the account of our DNA! Not only ours, i.e, humans, but all the species over the world. Many of the intellectual minds in our societies would think it okay with the technological progression; some would say that governments are preparing to control us, our minds.While many of you would be reading for the first time about the genomic industry!It is true that no technology comes without impacts or effects. But, is the storing of DNA data in the blockchain is correct or not is still an unanswered question.Therefore, I being in the IT and software industry decided to write this blog, “Can Blockchain Technology Effect The Genomics Industry?”NOTE: There are chances you might not conclude anything, but the confluence of blockchain & genome is a must-read.Let’s start and see the height of our medical researchers and software world!

Genomics And The Growth Of Technology

The demand of blockchain technology is high in every industry. And the genomic industry can’t neglect the fact that medical science and healthcare data industry need some secure place to store the results of their studies.That shows the importance of blockchain and its nature to store data.Conversely, the main question is why there is a need to store DNA data? If we go by the reports, the global Genomics industry by 2022 can reach to $24 billion market size that was $15 billion in 2017.Medical research on breaking the DNA code, programming DNA to make superhumans, and understanding our existence for betterment can be some reason that gave a sudden boom and heightened the interest in Genomes.As a result, many start-up companies are entering this market and are investing millions of money!23andMe (A genetic service provider) is one top-level genome testing company in USA with its major focus on collecting, analyzing, experimenting and synthesizing human genomic data.Roughly around two years ago, the company via Sequoia Capital raised a whopping amount of $250 million investment in the genomic industry.This much amount of money in DNA is enough to assume that in the coming ten years, we will see some historic breakthrough. Let’s face it as a positive side in the medical study!But, a large mob of people is against this DNA data collection and DNA study. Following which many genetic service provider companies are facing problems!

Data Policies & DNA Testing Companies

23andMe has been facing a backlash over its absolute data privacy policies.In June 2018, The Federal Trade Commission announced its investigation on many well-known DNA testing companies. The investigation though revealed data sharing with third parties, nothing happened, and everything remained on the paper with no action being taken.“In the investigation, 23andMe and Ancestry.com were also in the list of well-known companies.”On the other hand, where 23andMe is selling data for millions of dollars, customers are receiving nothing. This shows the breach and violation of data privacy.Given such unfairness and the increasing demand for this particular data, several promising start-ups are putting their entrepreneurial skills to protect users’ privacy and providing financial incentives for sharing it with researchers.It is a well-established fact, that our data is being taken for medical studies. More importantly, it is being transferred to others without our permission.What if the DNA studies, the genomic data gets hacked? I mean what if it falls in the wrong hands? This is a serious cybersecurity measure question.And blockchain technology is currently at the top when it comes to storing data securely and unhacked.

How Blockchain Is Impacting Genome Industry?

The genomic industry, companies like 23andMe, Illumina, Encrypgen (DNA), Luna DNA, Nebula Genomics, etc. use blockchain technology. Last year Encrypgen launched the world’s first public genomic data platform “Gene-Chain,” where consumers can securely upload & store their and their family’s genomic data for the benefit of a medical study.Furthermore, the user has all rights and freedoms to sell their data intentionally in exchange for money to the medical researchers. Here, researchers are data buyers who use their DNA tokens and give money to the users.Also, the last year in the U.S. Securities & Exchange Commission, Luna DNA’s DNA platform qualified to offer the share amount of money to the owner. Therefore, the Luna DNA became a major health data contributors.You might feel that this is a good option to give data and get money. However, it doesn’t look like that. It is because the money comes to you directly in cryptocurrencies like BTC and FIAT.Remember, we told you blockchain supports cryptocurrencies! Right from the start of data to money, everything is in favor of blockchain, genomic service providers, and blockchain.“Finally, is blockchain really impacting the genomics industry or we are being let unknown what really is going on with DNA.” My job ends here, I hope I created an interest in you to read more about the genome and blockchain before you make a conclusion by yourself.You can also write us down in the comment section below to discuss more about this topic. Otherwise, you can let us know something new related to this confluence of Genomes and Blockchain.I’ll be glad to write more about this!

Tags: